Endocrine Abstracts

Introduction: Adrenocortical carcicnoma (ACC) is a rare malignancy with overall incidence of 0.7–2.0 cases/million. It’s a rare & aggressive childhood cancer with a reported incidence of 0.2– 0.3 new cases per 1 million. It has Bimodal distribution - at first decade - 85% functional & 5-6th decade of life 15-30% functional. Paediatric virilising adrenal tumours have a better prognosis after complete resection than in adults. Surgery is the mai...

Background: Etiology of hypopituitarism differs in tropical countries compared to the West and includes pituitary abscess, snake bite, HIV infection, Sheehan syndrome, road traffic accidents, iron overload states etc.Aims and Objectives: The present case series highlights the spectrum of hypopituitarism in tropical countries.Case Details: 1. C1: 23 y/o female presented with loss of consciousness, unrecordable BP and hypoglycemia. H...

P450 Oxidoreductase (POR) deficiency is a rare autosomal recessive disorder of steroidogenesis with varied clinical presentation. POR is the electron donor for all microsomal enzymes involved in steroidogenesis namely P450c 17(17 hydroxylase/17,20 lyase), P450c 21 (21 –hydroxylase), and P450 aro(aromatase). POR deficiency can cause genital ambiguity in both sexes, impaired steroidogenesis and skeletal malformations. Here we present a patient with ovarian cysts and delayed...